Heartburn is the burning sensation you feel when stomach acid flows up into the esophagus. Certain foods, such as high-fat foods, spicy foods, acidic fruits, chocolate, alcohol, caffeinated drinks, and soda, as well as too much stress, are known to trigger heartburn. Nexium 24HR is indicated for the treatment of frequent heartburn (two or more days a week). With a once daily dose, Nexium gives you 24-hour relief from frequent heartburn caused by acid reflux. It’s simple to use. Just take one pill before eating in the morning (4). What can you imagine — waking up refreshed, trying new food on vacation, chocolate cake for two? Just one pill a day offers all-day, all-night protection (4) and reduces sleep interruptions from frequent heartburn (3). Get frequent heartburn off your mind, and live your life to the fullest. PPIs, or proton pump inhibitors like Nexium 24HR, treat frequent heartburn by blocking the production of acid at the source. PPIs may take 1-4 days for full effect, but remain effective over consecutive doses. H2s, or histamine blockers, block one of the signals that tell your body to make acid. They start working within 30 minutes and the effects can last for up to 12 hours, but become less effective if used for more than a few days in a row. Antacids neutralize stomach acid but do not reduce acid production at the source. Antacids work quickly, but effects last for only 1-3 hours after use. Do you frequently suffer from heartburn — the burning sensation you feel rising up through your chest & spreading toward your neck or throat, the sour & bitter taste in your mouth, the difficulty in swallowing? Frequent heartburn (caused by acid reflux) is a painful interruption to your day & can cause sleepless nights. With just one pill a day, Nexium 24HR stops acid before it starts for all-day, all-night protection from frequent heartburn.(4) The active ingredient in Nexium 24HR is esomeprazole 20mg, which is a part of a group of medications called proton pump inhibitors, or PPIs. PPIs stop heartburn at the source by turning off many of the pumps that produce acid. Imagine 24HRs without heartburn. Imagine waking up refreshed, enjoying pizza anytime, or not worrying about what to eat during a dinner party. Take Nexium 24HR once a day in the morning, & use as directed to treat frequent heartburn. Nexium 24HR pills may take one to four days for full effect. Available in capsules, tablets, or Clear Minis, Nexium 24HR is the brand doctors use most for their own frequent heartburn.(1) And with Amazon’s Subscribe & Save, you can enjoy routine deliveries of Nexium 24HR, & keep your medicine cabinet stocked(6).(1) Among PCPs who use a branded OTC PPI.(2) Among OTC brands. Based on IRI sales data 52 weeks ending 9/30/2018.(3) It's possible while taking Nexium 24HR. Use as directed for 14 days to treat frequent heartburn. Do not take for more than 14 days every 4 months unless directed by a doctor. Not for immediate relief.(4) Use as directed for 14 days to treat frequent heartburn. Nexium 24HR may take 1-4 days for full effect.(5) Use as directed for 14 days to treat frequent heartburn. Do not take for more than 14 days or more often than every 4 months unless directed by a doctor. If for any reason you are not satisfied with any GSK Consumer Healthcare product, GSK Consumer Healthcare will provide you with a reimbursement within 45 days of the date of purchase. Please note that because GSK is unable to control the quality of our products sold by unauthorized sellers, the Guarantee is not available for products purchased from unauthorized sellers due to potential quality issues outside GSK’s control. Please contact GSK Consumer Healthcare directly for more information. By Nexium Allergy alert: Do not use if you are allergic to esomeprazole Do not use if you have: Trouble or pain swallowing food, vomiting with blood, or bloody or black stools. Teartburn with lightheadedness, sweating or dizziness. Chest pain or shoulder pain with shortness of breath; sweating; pain spreading to arms, neck or shoulder; or lightheadedness. Please read packaging before use, for full list of warnings.Allergy Alert: Do not use if you are allergic to esomeprazole. Do not use if you have: trouble or pain swallowing food, vomiting with blood, or bloody or black stools, heartburn with lightheadedness, sweating or dizziness, chest pain or shoulder pain with shortness of breath, sweating, pain spreading to arms, neck or shoulders, or lightheadedness, frequent chest pain. These may be signs of a serious condition. See your doctor. Ask a doctor before use if you have had heartburn over 3 months, frequent wheezing, particularly with heartburn, unexplained weight loss, nausea or vomiting, stomach pain. This may be a sign of a more serious condition. Ask a doctor or pharmacist before use if you are taking warfarin, clopidogrel or cilostazol (blood-thinning medicines), prescription antifungal or anti-yeast medicines, digoxin (heart medicine), diazepam (anxiety medicine), tacrolimus or mycophenolate mofetil (immune system medicines), prescriptions antiretrovirals (medicines for HIV infection), methotrexate (arthritis medicine). Stop use and ask a doctor if, your heartburn continues or worsens, you need to take this product for more than 14 days, you need to take more than 1 course of treatment every 4 months, you get diarrhea. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children, in case of overdose, get medical help or contact a Poison Control Center right away. Do not use if seal under bottle cap imprinted with "sealed for your protection" or yellow band around the center of each capsule is broken or missing.Active Ingredients (in each capsule)...Purpose Esomeprazole 20mg... Acid Reducer (Each delayed-released capsule corresponds to 22.3mg esomeprazole magnesium trihydrate) Inactive Ingredients: Corn Starch, D&C Red No. 28, FD&C Blue No. 1, FD&C Red No. 40, Ferric Oxide, Gelatin, Glyceryl Monostearate, Hydroxypropyl Cellulose, Hypromellose, Magnesium Stearate, Methacrylic Acid Copolymer, Pharmaceutical Ink, Polysorbate 80, Sucrose, Talc, Titanium Dioxide, Triethyl Citrate.Adults 18 years of age and older. This product is to be used once a day (every 24 hours), every day for 14 days May take 1 to 4 days for full effect 14-Day Course of Treatment. Swallow 1 capsule with a glass of water before eating in the morning. Please read packaging before use, for full list of directions.EXPIRATION NOVEMBER 2015Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.